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Medicine General 26e811b6

The syndrome of inappropriate antidiuretic hormone is characterized by the following:

A
Hyponatremia and hyperkalemia
B
Hypernatremia and hypokalemia
C
Hyponatremia and urine sodium excretion >20 meq/1
D
Hypernatremia and urine sodium excretion>20 meq/1
High-Yield Explanation
Syndrome of inappropriate antidiuretic hormone is caused by excess secretion of vasopressin leading to increased absorption of water resulting in hyponatremia, inappropriate sodium secretion in the urine (> 20 mEq/L), hyper osmolar urine (>100mOsm/L) and hypo osmolar plasma (<260mOsm/L). Ref: The MD Anderson Manual of Medical Oncology, 2nd Edition, CHAPTER 46

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