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Medicine General 21ca0b4b

Cushing's disease is associated with:

A
Increased ACTH and increased coisol
B
Increased urinary Catecholamines
C
Increased ADH
D
Decreased ACTH and increased coisol levels
High-Yield Explanation
Answer is A (Increased ACTH and increased Coisol) Cushing's disease refers to increased production of Coisol (T Coisol) by Adrenals secondary to an ACTH producing tumor (1st ACTH) in the pituitary gland. It is thus associated with increased levels of ACTH and Coisol. Only an individual who has (increased coisol due to) an ACTH producing pituitary tumor is defined as having Cushing's disease, whereas Cushing's syndrome refers to all causes of excess coisol' - Harrison Increased urinary catecholamines is a feature of pheochromocvtoma and not Cushing's disease.

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