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Surgery Wounds, Tissue Repair & Scars 1baec617

Which of the following facilitates wound healing

A
Ascorbic acid
B
Zinc
C
Vitamin A
D
Selenium
High-Yield Explanation
(Ascorbic acid): (8-9- Das 7th edition; 24-25-Baily & Love 26th; 53-CSDT 13th)* Ascorbic acid used for common cold, wound healing, trauma, As an antioxidant provide some health benefits* Vit A is required for proper epithelialization. which may be hampered due to its deficiency* Zinc. Copper. Calcium and Manganese deficiency -Zinc is an essential component of many enzymes which are involved in protein synthesis. There is some failure of granulation tissue formation in case of zinc deficiency* Zinc is required for wound healing**. Zn enhances cell growth and divisions, besides stabilizing bio membanesKeshan disease (endemic cardiomyopathy) caused by selenium deficiencyAmong the following options ascorbic acid is the best correct answerLocal and Systemic Impediments to Wound healingSystemicLocal* Malnutrition* DM* Drugs (Steroids, cytotoxins)* Obesity* Shock* Immune deficiency* Renal failureWound infectionWound necrosisForeign bodiesWound hypoperfusion and hypoxiaRepeat traumaIrradiated tissueNeoplasm

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