In sickle cell trait, number of bands found in Hb-

In hemoglobin electrophoresis, various types of hemoglobin move at varying speed. In Sickle cell trait (heterozygous state), there are two types of hemoglobin : - HbS (40%) and HbA (60%). So, on electrophoresis, two different bands are produced. In homozygous state, almost all hemoglobin is HbS. So, a single band is produced. Laboratory findings of sickle cell anemia Moderate to severe anemia. Peripheral smear will show Sickle cells Target cells Howell-Jolly bodies because of autosplenctomy. A positive sickling test with a reducing substance like sodium metabisulfite.