Biochemistry Metabolism of lipid ffcc274f

Niemann-Pick disease occurs due to a defect in

Ceramidase

Sphinogomyelinase

Phospholipase C

b - galactosidase

High-Yield Explanation

DiseaseEnzyme DeficiencyClinical SymptomsNiemann-Pick diseaseSphingomyelinaseEnlarged liver and spleen, mental retardation;fatal in early lifeRef: Harper&;s Biochemistry; 30th edition; Chapter 24 Metabolism of Acylglycerols & Sphingolipids

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