Non competitive inhibition is
High-Yield Explanation
Features of noncompetitive inhibition
Inhibitor have no structural resemblance to substrate.
Mostly Irreversible (Except a few reversible non-competitive inhibition).
Excess substrate do not abolish the inhibition.
Km remains the same.
Vmax remains the same.
Features of competitive inhibition
Inhibitor will be structural analogue of substrate.
Reversible.
Excess substrate abolishes inhibition.
Vmax remains the same.
Km increases.