HLA is present on –
High-Yield Explanation
o HLA complex (MHC) gene is located on the short arm of chromosome 6.
o The histocompatibility antigens (human leukocyte antigens - HLA) are cell surface antigens that induce
an immune response leading to the rejection of allografts.
o The principal physiologic function of the cell surface histocompatibility molecules is to bind peptide
fragments of foreign proteins for presentation to antigen-specific T cells.
o The histocompa