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Pathology General ff2276eb

Which of the following changes in C-MYC oncogene may be associated with colonic malignancy?

A
Point mutation
B
Amplification
C
Rearrangement
D
Deletion
High-Yield Explanation
C- MYC amplification may be responsible for Ca breast, Ca colon, Ca stomach and lung. L - MYC amplification is associated with Ca lung and bladder. N- MYC amplification is associated with neuroblastoma and Ca lung. Ref: Harrison, 17th Edition, Page 496

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