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Medicine General feaead08

All are features of renal tubular acidosis type I, except :

A
Stone in kidney
B
No anion gap
C
Hypokalemia
D
Fanconi syndrome
High-Yield Explanation
Aswer is D (Fanconi syndrome): Fanconis Syndrome is an entity characterized by defective tubular reabsorption of most amino acids, glucose. urate, phosphate and bicarbonate. Defective tubular absorption of bicarbonate, with failure to transpo hydrogen ions causes a renal tubular acidosis producing hyperchloremic acidosis. Proximal A (A type II) is most often due to generalized proximal tubular dysfunction manifested by glycosuria aminoaciduria and phosphaturia (Fanconi's Syndrome) - Harrisons

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