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Surgery Breast feac064b

All of the following are poor prognostic markers of CA Breast except-

A
DNA aneuploidy
B
ER positivity
C
Her 2 neu positivity
D
p53 over expression
High-Yield Explanation
Ans. (b) ER positivity(Ref Schwartz 10th edition page 536)Poor Prognostic factors of Breast Cancer:Tumor related factorsHost related factors* Nodal status - Increased* Size and Grade of tumor - High* Lympho vascular invasion* Hormone Receptor- Negative* High Pathological staging* DNA Ploidy, S Phase fraction +* Her 2/neu overexpression* Intraductal component+* Young age* Menopausal status* Family History* Breast cancer History* Nutrition* Prior Chemotherapy and RT

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