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Pharmacology FMGE 2018 fe7f7e14

Exenatide is a new drug used in diabetes mellitus. Mechanism of action of this drug is:-

A
Inhibition of DPP- 4
B
Release of insulin acting as agonist of GLP-1 receptors
C
Inhibiting intestinal absorption of carbohydrates
D
Stimulation of PPAR-gamma
High-Yield Explanation
(a) Exogenous GLP-1 agonist --> Exenatide, Liraglutide --> given SC Analogues. (b) DPP-4 Inhibitors --> Sitagliptin, Vildagliptin --> given orally. (c) Inhibition of Intestinal absorption of carbohydrate --> Acarbose. (d) Stimulation of PPAR - gamma --> Piaglitazone, Rosiglitazone

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