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Medicine General fe43aecd

In a patient if administration of exogeneus vasopressin does not increase the osmolality of urine the likely cause is

A
SIADH
B
Psychogenic polydipsia
C
Renal Hyposensitivity to ADH
D
ADH Deficiency
High-Yield Explanation
Answer is C (Renal Hyposensitivity to ADH): Failure of urine osmolality to rise even after administration of exogenous ADH/vasopressin suggests a diagnosis of Nephrogenic Diabetes Insipidus due resistance to action of vasopressin on the Renal tubule (Renal Hyposensitivity to ADH).

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