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A five year old boy presents with precocious puberty and a blood pressure of 130/80 mmHg. Estimation of which of the following will help in diagnosis -

| 17 hydroxy-progesterone

| Cortisol

| Aldosterone

Renin

High-Yield Explanation

Ans- A. Ref- Nelson Textbook Of Pediatrics Vol. 1 20th ed Biochemical diagnostic studies show elevated levels of serum 17-OHP, the substrate for the defective 21-hydroxylase enzyme activity.

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A five year old boy presents with precocious puberty and a blood pressure of 130/80 mmHg. Estimation of which of the following will help in diagnosis -

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