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Pediatrics General fdcb8163

Which of the following is the least common cause of ambiguous genitalia in a female child –

A
Fetal placental steroid sulfatase deficiency
B
Fetal placental aromatase deficiency
C
Congenital adrenal hyperplasia
D
WNT–4 gene mutation
High-Yield Explanation
Placental steroid sufatase deficiency is an X-linked disorder (affects only males) that does not lead to ambiguous genitalia in a female child. 'Placental steroid suflatase deficiency is a rare X-linked disorder and all affected fetuses are males' William's 22nd/81 Congenital adrenal hyperplasia is the most common cause of ambiguous genitalia in female child. Fetal placental aromatase deficiency and WNT-4 gene mutation cause ambiguous genitalia in female child.

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