Which of the following statements regarding toxicity of local anesthetics is false?
High-Yield Explanation
Most allergic reactions are to aminoamide compounds * Slow injections limit the chance for local anesthetic toxicity. When history of allergy is unceain, an antihistamine such as diphenhydrarnine injected directly into the wound can be used as an alternative and achieves anesthesia in approximately 30 mm. * True allergic reactions to local anesthetics are rare, especially to aminoamide compounds such as lidocaine and bupivicaine. The ester derivatives of paraaminobenzoic acid, such as procaine, are responsible for most local anesthetic allergic reactions. * Toxicity should be suspected in patients who complain of dizziness, tinnitus, and periorbital tingling. Rarely, systemic convulsions follow. * These are usually self-limited because of rapid redistribution of the drug, with resultant lower serum levels.