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Pathology General fd0492e4

A 4-year-old male with mental retardation, self-mutilation, and hyperuricemia is likely to have a deficiency of an enzyme involved in the:

A
Conversion of homogentisic acid to methylacetoacetate
B
Degradation of galactocerebroside
C
Breakdown of branched-chain amino acids
D
Recycling of guanine and hypoxanthine
High-Yield Explanation
Adenosine deaminase is an enzyme that is deficient in individuals with the autosomal recessive form of SCID, and hypoxanthine-guanine phosphoribosyl transferase (HGPRT), an enzyme of the purine salvage pathway for recycling guanine and hypoxanthine that is deficient in individuals with the X-linked recessive disorder Lesch-Nyhan syndrome.

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