Which of the following chemotherapy agent can cause SIADH?
High-Yield Explanation
Neoplasms: Carcinoma - lung, duodenum, pancreas, ovary, Mesothelioma, Branchial adenoma, Carcinoid, Ewing sarcoma Head trauma Infections- Pneumonia, Abscess (lung or brain), Cavitation (aspergillosis), TB (lung or brain), Meningitis (Bacterial or viral) Encephalitis, AIDS Vascular: Cerebrovascular occlusions, hemorrhage, Cavernous sinus thrombosis Neurologic: GBS, MS, ALS, Delirium tremens, Hydrocephalus, Psychosis, Peripheral neuropathy. Metabolic: Acute intermittent porphyria Pulmonary: Asthma, Pneumothorax, Positive pressure ventilation Drugs: Vasopressin or Desmopressin, Chlorpropamide Oxytocin, high dose, Vincristine, Cyclophosphamide Carbamazepine, Phenothiazines, TCAs, Ref: katzung 12th ed.