Ectopic mucosa of Meckel's diveiculum is diagnosed by:
High-Yield Explanation
MECKEL'S DIVEICULUM Diagnosis Most accurate diagnostic test in children: Scintigraphy with sodium 99m Tc-peechnetate. The 99mTc-peechnetate is preferentially taken up by the mucus-secreting cells of gastric mucosa and ectopic gastric tissue in the diveiculum. (sensitivity-85%, specificity-95% and an accuracy-90 in the pediatric age group) Pentagastrin, H2 blockers and glucagon- enhance detection of ectopic gastric mucosa in Meckel's diveiculum by Tc-peechnate scan. Glucagon- relaxes the smooth muscles of GIT and decreases peristalsis. Pentagastrin- potent stimulator of gastric secretions, increases uptake and secretion of peechnetate by the gastric mucosa and stimulates gastrointestinal motility. Histamine H2 blockers (Cimetidine) block secretion from the cells and increase gastric mucosa uptake Less accurate in adults because of the reduced prevalence of ectopic gastric mucosa. In adult with normal nuclear medicine findings, barium studies should be performed.