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Pathology G.I.T fc4a9373

The genetic defect in Dubin-Johnson Syndrome is

A
Mutation in gene for multiple drug resistance protein 2
B
Mutation in gene UDP- glucuronyl transferase
C
Mutation of chromosome 23
D
Flash mutations
High-Yield Explanation
Dubin-Johnson syndrome is a rare, autosomal recessive, benign disorder that causes an isolated increase of conjugated bilirubin in the serum. Classically, the condition causes a black liver due to the deposition of a pigment similar to melanin. Refer robbins 9/e

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