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Biochemistry General fc42401f

Carbamoyl group of carbamoyl phosphate is derived from ?

A
Ammonia
B
Citrulline
C
Ornithine
D
Arginosuccinate
High-Yield Explanation
Ans. is 'a' i.e., Ammonia 1st reaction of urea cycle is synthesis of carbamoyl phosphate by condensation of ammonia (NH4') and CO2.The carbamoyl group of carbomoyl phosphate is derived from NH4. and a bicarbonate ion.The reaction is energetically demanding (two ATP) and is catalyzed by carbomoyl phosphate synthase LCPS-I is allosterically activated by N-acetyl glutamate.

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