C-ANCA positivity indicates, antibody formed against
High-Yield Explanation
C-ANCAs, or PR3-ANCA, or Cytoplasmic antineutrophil cytoplasmic antibodies, are a type of autoantibody, an antibody produced by the body that acts against one of its own protein . PR3 is the most common antigen target of ANCA in patients with granulomatosis with polyangiitis. Ref - Researchgate.net