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Commonest cause of Budd Chiary syndrome is:

A
Valve in the IVC
B
Hepatocellular carcinoma
C
Paroxysmal nocturnal hemoglobinuria
D
Renal cell carcinoma
High-Yield Explanation
Answer is C (Paroxysmal nocturnal hemoglobinuria): The most common cause of hepatic vein thrombosis from the list mentioned in Harrison is Paroxysmal nocturnal hemoglobinuria, and hence is the answer of choice here.

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