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Pathology General fbb0c32d

Acute phase reactants of inflammation are ?

A
Haptoglobin
B
C-reactive protein (CRP)
C
Transferrin
D
All
High-Yield Explanation
Ans. is 'a' i.e., Haptoglobin; 'b' i.e., C-reactive protein (CRP); 'c' i.e., Transferrin Acute phase proteins (reactants) Acute phase reactants are a class of proteins whose plasma concentration increases or decreases in response to inflammation. This response is called the acute phase reaction (acute phase response) It should be noted that acute phase proteins not only increase in response to inflammation ; some decrease also Proteins which increase in response to inflammation Positive acute phase proteins Proteins which decrease in response to inflammation --> Negative acute phase proteins 1. Positive acute phase proteins C-reactive protein (131-globulin) o a-2 microglobulin a-1 antitrypsin q Mannose binding protein o Fibrinogen, prothrombin, vWF o D-dimer protein Ferritin q Haptoglobulin 0 Serum amyloid A o Ceruloplasmin o Plasminogen, Factor VIII o Complement factors 2. Negative acute phase proteins 0 Albumin & Prealbumin u Transcoin o Transferrin o Retinol binding protein o Transthyretin

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