Fanconi's anemia is a –

Constitutional pancytopenia Constitutional pancytopenia is defined as decreased marrow production of the 3 major hematopoietic lineages on an inherited basis, resulting in anemia, neutropenia and thrombocytopenia. Important causes are : - Fanconi anemia                             o Amegakaryocytic thrombocytopenia Shwachman-Diamond syndrome      o Down syndrome Dyskeratosis congenita                   o Noonan syndrome