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Pharmacology Sympathetic System fafb0ff1

Dopamine is preferred over dobutamine in treatment of shock with oliguria because:-

A
It has additional renal vasodilatory effect
B
It increases cardiac output
C
It causes peripheral vasoconstriction only
D
It has prolonged action
High-Yield Explanation
Dopamine is the drug of choice for cardiogenic shock with oliguric renal failure. It acts on D1 (at a dose of 1-2 mg/kg/ min.), b1 (at 2-10 mg/kg/min.) and a1 (at > 10 mg/kg/min.) receptors. It causes renal vasodilation by acting on D1 receptors and maintains renal perfusion and GFR. Other ionotropic agents like NA cause renal vasoconstriction and thus worsen renal failure.

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