Pharmacology Chemotherapy fae8d756

All of the following statements about penicillin G are true EXPCEPT:

It is actively secreted in tubules

It is never administered orally

It is effective against gram positive as well as some gram negative bacteria

It acts by inhibiting cell wall synthesis

High-Yield Explanation

penicillin G is acid labile-destroyed by gastric acid. As such, less than 1/3rd of an oral dose is absorbed in the active form. Absorption of sod. PnG from i.m. site is rapid and complete; peak plasma level is attained in 30 min. ESSENTIALS OF PHARMACOLOGY page no. 718

← Previous Question Next Question →