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Pathology Haematology fad1c4c0

The translocation seen in follicular lymphoma is

A
T(11,14)
B
T(14,18)
C
T(9,22)
D
T(8,14)
High-Yield Explanation
Follicular lymphoma is a non-Hodgkin's lymphoma. When you havefollicular lymphoma, the sick blood cells can travel to many pas of your body, such as your organs, bone marrow, and lymph nodes (pea-sized glands in your neck, groin, and under your arms that are pa of your immune system Follicular lymphoma is a malignant counterpa to normal germinal B cells, and the majority of patients with this disorder show chromosomaltranslocation t(14;18)(q32;q21), which creates a derivative of chromosome 14 on which the BCL-2 gene is juxtaposed to immunoglobulin heavy-chain gene (IgH) sequence. Refer robbins 9/e

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