Biochemistry Metabolism of carbohydrate fa8e485d Niemann-Pick disease is due to deficiency of A Hexosaminidase B Sphingomyelinase C Galactokinase D Glucosidase High-Yield Explanation It is a lipid storage disease, due to deficiency of sphingomyelinase. Leads to the accumulation of sphingomyelin.Ref: DM Vasudevan, 7th edition, page no: 193