Microbiology General fa72a3bf Most common cause of Genital Herpes A HSV-1 B HSV-2 C HSV-3 (VZV) D HSV-4 (EBV) High-Yield Explanation Both HSV-1 and 2 can cause genital and oral - facial infection but reaction at oral - facial site is more common with HSV-1 and at the genital site with HSV-2