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Medicine G.I.T fa689456

A 30 year old lady presents with features of malabsorption and iron deficiency anemia. Duodenal biopsy shows complete villous atrophy. Which of the following antibody is likely to be present.

A
Antiendomysial antibodies
B
Anti-goblet cell antibodies
C
Anti-Saccharomyces cerevisae antibodies
D
Antineutrophil cytoplasmic antibodies
High-Yield Explanation
IgA anti-endomysial antibodies are found in 90% coeliac patients. They are a very specific & sensitive marker for coeliac disease and dermatitis herpetiformis. The anti-endomysial antibody test has been suggested to be 98% sensitive and 98% specific for clinical or subclinical coeliac disease Ref Davidson edition23rd pg 805

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