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Skin Vesiculobullous (Blistering) Disorders fa4d1794

Row of tombstone is seen in which skin disorder:

A
Pemphigus vulgaris
B
Pemphigus foliaceous
C
Paraneoplastic pemphigus
D
Bullous pemphigoid
High-Yield Explanation
Ans. A. Pemphigus vulgaris* Pemphigus vulgaris is characterized by following signs:1. Bulla spread sign2. Perilesional, and distant Nikolsky sign3. Tzanck smear: Acantholytic cell* Histopathology shows suprabasal blister with row of tomb stone appearance of basal cells.* Direct immunofluorescence from perilesional skin demonstrated intra epidermal IgG deposits' in a fishnet pattern.

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