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Medicine General fa192b80

Fatal familial insomnia is associated with :

A
Prion disease
B
Degenerative disease
C
Neoplastic disease
D
Vascular disease
High-Yield Explanation
Answer is A (Prion Disease): Fatal familial insomnia is one of the commonly caused prion disease. PRIONS refer to a class of proteinacious infectious paicles without any detectable nucleic acid i.e. 'virus like paicles without the nucleic acid components'. - Ananthnarayan 6th /416 As can be expected they are sensitive to proteasesQ (contain protein) but resistant to nucleasese (do not contain nucleic acid) as well as to heat & UV rays. The most commonly caused prion diseases include`: Kura Creutzfeildt - Jakob diseaseQ Gestermann - Straussler - Scheinker syndrome Q Fatal familial insomnia Q

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