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Biochemistry HAEM synth and porphyrias fa14c2c8

Which of the following inborn error of metabolism has porphyria like clinical features?

A
Phenylketonuria
B
Tyrosinemia type I
C
Alkaptonuria
D
Metachromatic leukodystrophy
High-Yield Explanation
Succinylacetone accumulates in hereditary tyrosinemia type I (fumarylacetoacetate hydrolase deficiency). Succinylacetone is structurally similar to ALA and inhibits ALA dehydratase leading to porphyria like features.

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