Increased nuchal translucency at 14 weeks of gestation is seen in:

First-trimester screening at 11 to 14 weeks' gestation, using the fetal nuchal translucency measurement together with serum analytes like PAPP-A and HCG levels , has achieved Down syndrome detection rates comparable to those for second-trimester screening in women younger than 35 years. It is measured in the sagittal plane between 11 and 14 weeks, when the crown-rump length measures between 38 and 84 mm. Increased fetal nuchal thickness is a strong marker for chromosomal anomalies in the first trimester. Increased fetal nuchal translucency i.e. > 3 mm on ultrasound is suggestive of trisomies