Nissl bodies in neurons are

Nissl bodies are basophilic bodies or granules composed of many thin, parallelly arranged, membrane-bounded cavities or cisternae which are covered by many minute paicles consisting of Ribose nucleoproteins i.e. RNA with proteins. Granule&;s size and number vary with physiological condition of the cell. For example, fatigue, ceain poisons, and sectioning of axon cause Nissl granules to disintegrate into fine dust and which finally disappears.Ref: Textbook of physiology, Dir. Prof. AK Jain, 5th edition.