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Pharmacology Hematology f9548933

All are true about warfarin, except

A
It inhibits the activation of vitamin K dependent cloting factors
B
Its half life is 36 hours
C
It can cross placenta
D
Its dose is increased in liver disease
High-Yield Explanation
It&;s dose should be reduced in liver and renal impairment as it is metabolized by glucoronide conjugation and is excreted by urine. From medical pharmacology padmaja 4th edition Page no 339,341

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