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Medicine Virology f9448e51

Treatment of choice for HIV and TB along with Rifampicin is?

A
Saquinavir
B
Nevirapine
C
Ritonavir
D
Amprenavir
High-Yield Explanation
ANSWER: (C) RitonavirREF: Harrisons 17th ed chapter 182Ritonavir has a high affinity for several isoforms of cytochrome P450, and its use can result in large increases in the plasma concentrations of drugs metabolized by this pathway. Rifampicin is metabolized by the pathway and hence ritonavir used with rifampicin in TB and HIV.

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