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Pharmacology General f93f0e5c

Which of the following is a prokinetic drug?

A
Domperidone
B
Cimetidine
C
Ondansetron
D
Hyoscine
High-Yield Explanation
Ans. is 'a' i.e., Domperidone Gastrokinetic (prokinetic drugs) These are the drugs which promote gastrointestinal transit and speed gastric emptying by enhancing coordinated propulsive motility. Prokinetic drugs are - Metoclopramide, Domperidone, Cisapride, Mosapride, Tegaserod, renzapride, prucalopride. Prokinetic drugs can act by ? 5HT4 agonistic activity D2 and 5-HT3 antagonistic activity Both these actions will increase the release of Ach and thereby motility of GIT.

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