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Pharmacology General f9393fb8

Pegloticase used in treatment of gout acts by which of the following mechanism:

A
It inhibits Xanthine oxidase enzyme
B
It metabolizes uric acid to allantoin
C
It inhibits the migration of inflammatory cells
D
It accumulates in synovial fluid and prevent the action of cytokines
High-Yield Explanation
Rasburicase and Pegloticase metabolize insoluble uric acid to soluble allantoin and used in the treatment of chronic gout.

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