Pharmacology General f9393fb8 Pegloticase used in treatment of gout acts by which of the following mechanism: A It inhibits Xanthine oxidase enzyme B It metabolizes uric acid to allantoin C It inhibits the migration of inflammatory cells D It accumulates in synovial fluid and prevent the action of cytokines High-Yield Explanation Rasburicase and Pegloticase metabolize insoluble uric acid to soluble allantoin and used in the treatment of chronic gout.