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Microbiology General f7e94370

All of the following are true about V. cholerae 0139 except:

A
Clinical manifestations are similar to 01 El tor
B
First discovered in Chennai
C
Produces 0139 lipopolysaccharide
D
Epidemiologically indistinguishable from 01 El tor
High-Yield Explanation
Ans. (b) First discoverd in Chennai Guy's before solving this question, you must understand the epidemiology of cholera. Vibrio cholerae I 01 Type Non 01 (NAG) Classical El tor 0139 Bengal (Responsible for first six (Responsible for - Proposed agent pandemic of cholera) seventh pandemic) for 8th pandemic infuture In 1992, after its isolation 0139 had initially replaced E, tor and become the most common causative agent of cholera in South Asia. However, by the beginning of 1994 E, tor had resumed its dominance in many areas and above all 0139 has not spreaded outside Asia The clinical manifestation and epidemiological features of the disease caused by V. cholerae 0139 are indistinguishable from those of 01 cholera. 0139 V. cholerae is identical to E, tor except for two impoant differences: Production of novel 0139 Lipopolysaccharide. Immunologically related 0 antigen polysaccharide capsule. Remember: E, tor biotype was first isolated at the E, tor quarantine station in Egypt in 1905. - Presently most cases of cholera are caused by E1 tor.

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