IV thrombolysis is of no use in ischaemic stroke beyond

In IV PA trails, efficacy was confirmed in the <3-h time window, and efficacy likely extended to 4.5 h and possibly to 6 h.Depending on the country, IV PA is approved for up to 4.5 hCriteria for administration of Intravenous Recombinant Tissue Plasminogen Activator (PA ) for Acute Ischemic Stroke (AIS)Clinical diagnosis of strokeOnset of symptoms to time of drug administration <=4.5 hCT scan showing no haemorrhage or edema of >1/3 of the MCA territoryAge 18 >= yearsConsent by patient or surrogateRef: Harrison 19e pg: 2562