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Physiology Renal physiology f6fdb820

Which of the following renal alterations would most likely preserve the GFR?

A
Defect in the elimination of hydrogen ions in the distal tubule
B
Luminal obstruction by renal tubular casts
C
Increased interstitial pressure
D
Decreased intrarenal nitric oxide
High-Yield Explanation
The renal alteration that would most likely preserve the GRF is type I distal renal tubular acidosis, in which hydrogen ions diffuse back into the distal tubule. This not only retains hydrogen ions, but also reduces the distal tubule reabsorption of bicarbonate. The other choices listed are assocated with acute tubular necrosis and decrease the GFR.

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