Surgery Miscellaneous (Parathyroid & Adrenal Glands) f6d69794 Parathyroid adenoma most commonly involves which of the following sites:-- A Thyroid substance B Superior parathyroid lobe C Inferior parathyroid lobe D In the mediastinum High-Yield Explanation Ans 'c' i.e. inferior parathyroid lobe .Parathyroid adenomas most commonly involves the inferior parathyroid glands.