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Pharmacology Autacoids f669f208

Aspirin should be used with caution in the following groups of patients because of which of the following reason:

A
In diabetics because it can cause hyperglycemia
B
In children with viral disease, because of the risk of acute renal failure
C
In gout, because it can increase serum uric acid
D
In pregnancy, because of high risk of teratogenicity
High-Yield Explanation
Aspirin- Urate excretion: Aspirin in high dose reduces renal tubular excretion of urate- dose more than 5 grams per day- that is more than the antiinflammatory dose ESSENTIALS OF MEDICAL PHARMACOLOGY;7TH EDITION; KD TRIPATHI; PAGE NO 195

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