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Medicine C.V.S f648389a

Aggrevation of symptoms of angina in a patient when given nitrates is seen in

A
Aoic regurgitation
B
Mitral regurgitation
C
Single left coronary aery stenosis
D
Idiopathic hyperophic subaoic stenosis
High-Yield Explanation
Ref Harrison 19 th ed pg 1568 Idiopathic hyperophic cardiomyopathy ( HOCM) is a dynamic outflow obstruction which is increased by any mechanism decreasing the preload . Nitrates decrease the preload,the volume of blood in LV and thereby increase the dynamic obstruction and symptom of angina

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