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Pediatrics General f5f4b265

All of the following conditions have autosomal dominant inheritance except –

A
Fabry's disease
B
Marfan's syndrome
C
Osteogenesis imperfecta
D
Ehlers Danlos syndrome
High-Yield Explanation
Autosomal dominant disorders Normally a gene pair has two alleles. When one allele becomes abnormal due to mutation it is called heterozygous state. When both the alleles become abnormal due to mutation it is called homozygous state. Autosomal dominant disorders are manifested in heterozygous state, i.e. only if one allel is abnormal the disease will be manifested. Autosomal dominant disorders

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