Gynaecology & Obstetrics
Medical, surgical and gynaecological illness complicating pregnancy
f50b0c05
True about MgSO4
High-Yield Explanation
The drug of choice for control and prevention of convulsion in eclampsia is magnesium sulphate ,usually given by Pritchard&;s regime.The mechanism of action thought to have a peripheral action at the neuromuscular junction,by competing with calcium for entry into the cells.It may also have central action.It is used as tocolytic also.in case of magnesium toxicity,there can be respiratory depression.Absolute contraindications are Myasthenia gravis and myocardial infarction. TEXT BOOK OF OBSTETRICS,Sheila Balakrishnan,2nd edition,page no.268