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General Medicine General f4e07f0b

True about protease inhibitors are all EXCEPT :

A
Acts as a substrate for P–glycoprotein (P–gp) and action is mediated by MDR1 gene
B
Undergo hepatic oxidative metabolism
C
Protease inhibitors interfere with metabolism of several drugs
D
Saquinavir causes maximum induction of CYP3A4

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