A patient having glaucoma develops blepharoconjunctivitis after instilling some antiglaucoma drug. Which of the following drug can be responsible for it –

Ocular side effects of topical agents for POAG β-blockers : Allergic blepheroconjunctivitis, corneal hyposthesia, Blurred vision, Dryness of eye, superficial punctate keratitis. Cholinomimetics (Pilocarpine) : Blurred vision, miosis, accommodative spasm, browache. Symathomimetics : Non-selective (Dipivefrine) :- Follicular conjunctivitis, rebound congestion, macular edema in aphakic. Brimonidine: - Conjunctival blanching, ocular allergy. Apraclonidine: - Allergies, fluctuation in visual acuity. Carbonic anhydrase inhibitors (Dorzolamide, Brinzolamide) Punctate keratitis, ocular allergies. Prostaglandin analogues (Latanoprost) Punctate keratitis, iris pigmentation.