Full 2L QBank
Pathology General f4a444e4

Notch effect in embryogenesis is an example of which type of signalling?

A
Autocrine
B
Paracrine
C
Endocrine
D
None of the above
High-Yield Explanation
One cell type produces the ligand, which then acts on adjacent target cells that express the appropriate receptor. The responding cells are in close proximity to the ligand-producing cell and are generally of a different type. Paracrine stimulation is common in connective tissue repair of healing wounds, in which a factor produced by one cell type (e.g., a macrophage) has a growth effect on adjacent cells (e.g., a fibroblast). It is also necessary for hepatocyte replication during liver regeneration and for Notch effects in embryonic development, wound healing, and renewing tissues. Ref: Robbins 8th edition, Chapter 3

Related Pathology MCQs

Practice 2,00,000+ NEET PG Questions Free

Timed mock tests, mistake queue analytics, audio lectures & zero attempt limits on i❤️Exams.

Start Free Mock Test Now